Chinese Medicine Times : Keeping You Informed

Chinese Medicine Times : Keeping You Informed

Chinese herb regulates inflammation

Source: http://www.upi.com/Health_News/2012/02/29/Chinese-herb-regulates-inflammation/UPI-37451330576200/

U.S. scientists have discovered the molecular secrets behind a Chinese herb's extract made from Chang Shan, a type of hydrangea that grows in Tibet and Nepal.

Senior author Malcolm Whitman, a professor of developmental biology at Harvard School of Dental Medicine, said for roughly 2,000 years, Chinese herbalists have treated malaria using a root extract, commonly known as Chang Shan.

Recent studies suggested that halofuginone, a compound derived from this extract's bioactive ingredient, could be used to treat many autoimmune disorders as well.

"It turns out that halofuginone triggers a stress-response pathway that blocks the development of a harmful class of immune cells, called Th17 cells, which have been implicated in many autoimmune Whitman said in a statement. "Halofuginone prevents the autoimmune response without dampening immunity altogether. This compound could inspire novel therapeutic approaches to a variety of autoimmune disorders."

Scientists have only recently appreciated the role of the nutrient sensing-amino acid response pathway, a pathway in immune regulation and metabolic signaling.

The amino acid response pathway lets cells know when they need to preserve resources. For example, when a cell senses a limited supply of amino acids for building proteins, the amino acid response pathway will block signals that promote inflammation because inflamed tissues require lots of protein, Whitman said.

The findings were published in the Nature Chemical Biology.

 

Back To Latest Articles and News

Email This Page
Discuss This

Subscribe To CMT

Shopping Basket

Your basket is empty!

Recently Viewed Login Register

Change Language

Change Currency

Subscribe to our RSS Feed Chinese Medicine Times Facebook Fan Page Chinese Medicine Times Twitter Page Chinese Medicine Times Linkedin Page Email a friend about this website
  • All about Natural Medicine Advert 10-09-2014
  • AcuGlide Needle Offer
  • Acumaster Offer
  • Vinco Needle Offer
  • Viva Offer

Events Calendar

Master Tung's Acupuncture: Five Zang System by Dr. Chuan-Min Wang (11/2/2014)

WEBINAR: Join Dr. Chuan-Min Wang, a direct disciple of the famous Master Tung Ching-Chang... [more]

The Best of Master Tung's Magic Points with Susan Johnson (11th-12th October 2014)

Susan Johnson's favorite acupuncture points in Master Tung's... [more]

View Events Calendar

From Our Store

Replacement Dongbang 7 Star Hammer Heads

Replacement Dongbang 7 Star Hammer Heads

Two Dongbang 7 star acupu...
Dongbang Smokeless Moxa

Dongbang Smokeless Moxa

Smokeless and odour free ...
Kidney Tray - Medium

Kidney Tray - Medium

Kidney trays are kidney s...
Gua Sha Rod - Horn Shaped

Gua Sha Rod - Horn Shaped

Horn shaped gua sha tool
The Essential Woman

The Essential Woman

by Elisabeth de la Vallee