Chinese Medicine Times : Keeping You Informed

Chinese Medicine Times : Keeping You Informed

Acupuncture compared with oral antihistamine for type I hypersensitivity itch and skin response in adults with atopic dermatitis

Source: http://onlinelibrary.wiley.com/doi/10.1111/j.1398-9995.2012.02789

Abstract

Background

Itch is the major symptom of atopic dermatitis (AD). Acupuncture has been shown to exhibit a significant effect on experimental itch in AD. Our study evaluated acupuncture and antihistamine itch therapy (cetirizine) on type I hypersensitivity itch and skin reaction in AD using a patient and examiner-blinded, randomized, placebo-controlled, crossover trial.

Methods

Allergen-induced itch was evaluated in 20 patients with AD after several interventions in separate sessions: preventive (preceding) and abortive (concurrent) verum acupuncture (VAp and VAa), cetirizine (10mg, VC), corresponding placebo interventions (preventive, PAp, and abortive, PAa, placebo acupuncture; placebo cetirizine pill, PC) and a no-intervention control (NI). Itch was induced on the forearm and temperature modulated over 20min, using our validated model. Outcome parameters included itch intensity, wheal and flare size and the D2 attention test.

Results

Mean itch intensity (SE: 0.31 each) was significantly lower following VAa (31.9) compared with all other groups (PAa: 36.5; VC: 36.8; VAp: 37.6; PC: 39.8; PAp: 39.9; NI: 45.7; P<0.05). There was no significant difference between VAp and VC (P>0.1), although both therapies were significantly superior to their respective placebo interventions (P<0.05). Flare size following VAp was significantly smaller (P=0.034) than that following PAp. D2 attention test score was significantly lower following VC compared with all other groups (P<0.001).

Conclusions

Both VA and cetirizine significantly reduced type I hypersensitivity itch in patients with AD, compared with both placebo and NI. Timing of acupuncture application was important, as VAa had the most significant effect on itch, potentially because of counter-irritation and/or distraction. Itch reduction following cetirizine coincided with reduced attention.

Back To Latest Articles and News

Email This Page
Discuss This

Subscribe To CMT

Shopping Basket

Your basket is empty!

Recently Viewed Login Register

Change Language

Change Currency

Subscribe to our RSS Feed Chinese Medicine Times Facebook Fan Page Chinese Medicine Times Twitter Page Chinese Medicine Times Linkedin Page Email a friend about this website
  • Chinese Herbal Formulas: Treatment Principles and Composition Strategies
  • Cupping Advert General
  • The Treatment of Pain with Chinese Herbs and Acupuncture, 2nd edition
  • AcuGlide Needle Offer
  • Acumaster Offer
  • Vinco Needle Offer
  • Viva Offer

Events Calendar

Auricular Medicine Class II: Auricular points by Dr.Li-Chun Huang (12/6/14-12/7/14)

WEBINAR: The human ear is a poweful tool for both diagnosis and treatment... [more]

National Acupuncture Detox Association Protocol Training ( April 25th-27th)

Thousands of behavioral health treatment and criminal justice... [more]

View Events Calendar

From Our Store

Teaching Atlas of Acupuncture Vol1 & 2

Teaching Atlas of Acupuncture Vol1 & 2

by Pierro Quirico and Tiz...
Straight Ear Probe

Straight Ear Probe

Stainless steel straight ...
Couch Roll - Blue - 9 Rolls

Couch Roll - Blue - 9 Rolls

Full 20"/508mm wide couch...
Dongbang Magnets

Dongbang Magnets

Magnets for acupuncture a...